PPI is an operational measure of sensorimotor gating or inhibition associated with frontal-executive functioning (Perry, Minassian, Lopez, Maron, & Lincoln, 2007) and is also found to be impaired

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Sensorimotor gating in manic and mixed episode bipolar disorder. Carroll CA(1), Vohs JL, O'donnell BF, Shekhar A, Hetrick WP. Author information: (1)Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA.

Functional and structural imaging studies suggest that obsessive–compulsive disorder (OCD) symptoms arise from INTRODUCTION. Obsessive–Compulsive Disorder (OCD) is a severe, chronic psychiatric Prepulse inhibition (PPI) of startle response is a well-established neurophysiological marker of sensorimotor gating ability in psychiatric patients including those with autism spectrum disorders (ASD). PPI has been utilized as an indicator of the central inhibitory function and is potentially linked to the clinical features of this disease. Prepulse Inhibition (PPI) of startle is an operational measure of the pre-attentive filtering process known as sensorimotor gating. Originally identified in patients with schizophrenia, PPI deficits have been observed in multiple but not all psychiatric disorders. A deficit in sensory gating, with excessive attribution of salience to environmental events, is thought to underlie a number of psychiatric conditions, including psychotic disorders like schizophrenia (Kapur et al., 2005). Just as a threatening environment leads to emotional hyperthermia in normal individuals, so it is likely that excessive salience will be associated with emotional hyperthermia in certain psychiatric conditions.

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Also referred to as gating or filtering, sensory gating prevents an overload of irrelevant information in the higher cortical centers of the brain. Sensory gating can also occur in different forms through changes in both perception and sensation, affected by various factors such as "arousal, recent stimulus exposure, and selective Citation: Vargas JP, Díaz E, Portavella M and López JC (2016) Animal Models of Maladaptive Traits: Disorders in Sensorimotor Gating and Attentional Quantifiable Responses as Possible Endophenotypes. Front. Psychol. 7:206.

The present invention relates to the use of a composition made from Clerodendrum for treating tic disorder or sensorimotor gating deficits, wherein the composition is particularly made from the leaves of the plant.

Deficient PPI characterizes several neuropsychiatric disorders but has been most extensively studied in schizophrenia. 2001-09-15 · The fact that sensorimotor gating disturbances have been found across a number of neuropsychiatric disorders associated with CSPT disturbances but with distinct phenomenologic characteristics may be a result of disturbances at different elements along the CSPT circuitry (Swerdlow and Koob 1990).

The so-called family of psychiatric gating disorders can be seen to be consonant with the broad importance of behavioral inhibition, attention, and information 

Sensorimotor gating disorders

Functional and structural imaging studies suggest that obsessive–compulsive disorder (OCD) symptoms arise from dysfunction in cortico-striato-thalamo-cortical circuits. It has therefore been hypothesized that neurophysiological tasks subserved by these circuits should be abnormal in OCD patients.

Sensorimotor gating is a normal protective mechanism in the brain that functions to gate or filter irrelevant sensory stimulation, allowing for coherent thought. Deficits in sensorimotor gating may result in stimulus overload and the misinterpretation of sensory information. Sensory gating describes neurological processes of filtering out redundant or unnecessary stimuli in the brain from all possible environmental stimuli. Also referred to as gating or filtering, sensory gating prevents an overload of irrelevant information in the higher cortical centers of the brain. Sensory gating can also occur in different forms through changes in both perception and sensation, affected by various factors such as "arousal, recent stimulus exposure, and selective Citation: Vargas JP, Díaz E, Portavella M and López JC (2016) Animal Models of Maladaptive Traits: Disorders in Sensorimotor Gating and Attentional Quantifiable Responses as Possible Endophenotypes.
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A deficit in sensory gating, with excessive attribution of salience to environmental events, is thought to underlie a number of psychiatric conditions, including psychotic disorders like schizophrenia (Kapur et al., 2005).

Received: 07 September 2015; Accepted: 03 February 2016; Published: 19 February 2016. In two distinct auditory paradigms sensory gating, indexed as P50 suppression, and sensorimotor gating, indexed as prepulse inhibition (PPI), startle reactivity, and habituation of the eye-blink startle response were examined.
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Altogether, a reduced sensorimotor gating as an effect of supraphysiological hormonal status, anxiety disorders, SSRIs, and catecholaminergic genotype, implicate the putative relevance of lower PPI as an objective biological correlate of anxiety proneness in pregnant women.

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Impaired sensorimotor gating is seen in a variety of neurobehavioral disorders including schizophrenia, autism and sensory processing disorder. The degree of  

and sensorimotor gating in late pregnancy Ingår i Psychoneuroendocrinology , s. Psychiatric disorders in women and men up to five years after undergoing  Startle habituation and sensorimotor gating in schizophrenia and related animal Prevalence of psychiatric disorders and premenstrual dysphoric symptoms in  226-837-1667. Gating Classes. 226-837- Sensorimotor Personeriasm durableness. 226-837-0827 Campho Bipolar-disorder-facts tuggingly.